What is Pasteurella haemolytica and Pasteurella multocida?

Two members of the Pasteurellaceae family, Mannheimia haemolytica (formerly Pasteurella haemolytica biotype A) and Pasteurella multocida, represent major bacterial causative agents of respiratory disease in cattle, which are frequently associated with BRD (Confer, 2009, Griffin et al., 2010, Rice et al., 2007).

How do you identify Pasteurella multocida?

The Minitek identification of Pasteurella depends on 100% positive xylose reactions, whereas only 56% of the P. haemolytica strains were positive for xylose fermentation. The Oxy/Ferm system, instead of giving a definitive identification, in most instances merely placed Pasteurella in a category of similar organisms.

Does Pasteurella grow on MacConkey?

They do not grow on MacConkey agar. They are usually oxidase positive and also positive for nitrate reduction, phosphatase, β-galactosidase and acid production from D – Glucose fermentation. They are negative for catalase, indole, urease, Voges-Proskauer and methyl red tests.

How is Pasteurella multocida transmitted?

Pathogenicity. Pasteurella multocida is transmitted to humans by contact with infected animals, usually following bites or scratches from cats or dogs. Respiratory tract infections may occur through airborne transmission (see Chapter 73). Occasionally, an animal source of infection is not documented.

How is Mannheimia Haemolytica treated?

It involves a combination of two therapies in one dose: the powerful antibiotic florfenicol to kill or inhibit the disease-causing bacteria Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis; and, the fast-acting non-steroidal anti-inflammatory drug (NSAID) flunixin meglumine to …

What is Pasteurella sepsis?

Pasteurella multocida colonizes animal scratches and bites. This bacterium was described to cause sepsis or endocarditis mainly in immunocompromised patients. We report the case of a 92-year-old woman presenting at the Emergency Department with coma and fever a week after the bite of her cat.

How do I identify Pasteurella?

The Pasteurella species are spherical, ovoid or rod-shaped cells 0.3-1.0µm in diameter and 1.0-2.0µm in length. Cells are Gram negative, and occur singly, or in pairs or short chains. Bipolar staining may be seen and capsules may be present. All species are non-motile, and are facultatively anaerobic.

Is Pasteurella a lactose fermenter?

It was observed that vaccinal strain of Pasteurella multocida fermented glucose, Sucrose ,Maltose, Galactose , Mannose and Fructose but did not ferment lactose and salacin. It did not liquefy gelatin. the investigation, various types of the colonies of the organism were also observed on blood agar.

What kills Pasteurella multocida?

The drug of choice for known P multocida is penicillin, but rare β-lactamase–producing strains have been isolated. Oral agents that usually are effective against P multocida include amoxicillin, cefuroxime, cefixime, cefpodoxime, doxycycline, and fluoroquinolones.